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Non-Human

ZOO FISH v2

For information regarding products soon to be available in the Cytocell ZooFISH probe range, or to discuss your requirements for a custom ZooFISH probe, please email probes@cytocell.com

ZOO FISH Range

Cytocell has developed FISH probes for the following species:

ZooFISH combinedChromoprobe Multiprobe OctoChrome Murine*

Murine magnified

The Cytocell Chromoprobe Multiprobe OctoChrome Murine (OctoChrome Murine) is designed to identify aneuploidies and translocations present in the entire mouse karyotype. The system utilises mouse whole chromosome Painting (WCP) probes directly labelled in 3 different colours, which allows the visualisation of chromosomal abnormalities under the fluorescence microscope without expert knowledge of the mouse karyotype.

Murine device layout large

Figure 1: The OctoChrome Murine device layout. Each square of the OctoChrome Murine device carries mouse whole chromosome painting probes for three different chromosomes labelled in red, green and aqua blue (Texas Red®, FITC and aqua spectra, respectively); these probes are reversibly dried on to the first 7 squares of the device using a proprietary process. FISH signals are visible simultaneously with a DAPI/FITC/Texas Red® triple filter or individually through specific single fluorescence filters.

Chromoprobe Multiprobe Porcine*

Porcine magnified

The Cytocell Chromoprobe Multiprobe Porcine is a useful tool in the pig breeding industry to identify translocations that have implications in fertility. The system allows the user to perform multiple FISH experiments on a single slide and to detect chromosomal aberrations (aneuploidy, chromosome breakage and rearrangements) present in the pig karyotype. The Chromoprobe Multiprobe Porcine utilises directly-labelled locus-specific subtelomere BAC probes, allowing the visualisation of any chromosomal aberrations under the fluorescence microscope without expert knowledge of the pig karyotype.

Porcine device layout large

Figure 2: The Chromoprobe Multiprobe Porcine device layout. Each square of the device carries two subtelomeric BAC probes labelled in red and green fluorochromes (Texas Red®, FITC). The probes are reversibly dried on to the first 19 squares of the device using a proprietary process. FISH signals are visible with a DAPI/FITC/Texas Red® triple filter or individually through specific single filters.

Chromoprobe Multiprobe Chicken*

Chicken magnified

The chicken genome consists of a large number of microchromosomes; therefore, analysis of the chicken genome by classical cytogenetics is extremely complex. The Cytocell Chromoprobe Multiprobe Chicken is designed to identify complex chromosome rearrangements present in the chicken karyotype* (1-28, Z and W). The system utilises directly-labelled whole chromosome painting (WCP) probes and locus-specific subtelomere BAC probes that allow the visualisation of chromosomal rearrangements under the fluorescent microscope without expert knowledge of the chicken karyotype.

Chicken device layout large

Figure 3: The Chromoprobe Multiprobe Chicken device layout. Each square of the devices carries either chicken chromosome paints for three different chromosomes (macro) labelled in red, green and aqua (Texas Red®, FITC and aqua spectra, respectively); or subtelomeric BAC probes labelled in red and green fluorochromes (Texas Red®, FITC). The probes are reversibly dried on to the first 23 squares of the device using a proprietary process. FISH signals are visible with a DAPI/FITC/Texas Red® triple filter or individually through specific single fluorescence filters.

Custom ZOO Probes

Cytocell offers a custom design and build service to produce unique FISH probes using our BAC-2-FISH™ process. This exciting service enables the creation of personalised probes that meet your specific needs. Contact us for more information.

*For research use only, not for use in diagnostic procedures. 

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