13q14.3 Deletion LPH006

From Acute Lymphoblastic Leukaemia to Multiple Myeloma and non-Hodgkin's Lymphoma, deletions in 13q14 are common in B-cell neoplasms. Deletions are observed in 30% of karyotypically normal Multiple Myeloma patients and in over 20% of B-cell Chronic Lymphocytic Leukaemia (CLL) patients. A further 20% have microscopic deletions and 10% exhibit homozygous loss.