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BCL6 Breakapart LPH035
Rearrangements of the BCL6 gene have been observed in 20-40% of diffuse large B cell lymphoma (DLCL) and in 5-15% of follicular lymphoma (FL) resulting in the deregulation of BCL6. BCL6 functions as a transcriptional repressor and plays an important regulatory role in lymphoid cell development and function. Recently an alternative breakpoint cluster region (ABR) was identified in Non-Hodgkins Lymphomas (NHL) which may be preferentially associated with Follicular Lymphoma.
BCL6 Breakapart Probe
Cat. No. LPH 035-S (5 tests)
Cat. No. LPH 035 (10 tests)
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