Alagille (JAG1) Probe LPU012

Alagille syndrome (AGS) is an autosomal dominant disorder characterised by abnormalities of the liver, heart, skeleton, eyes and face. Disruption of the Jagged1 gene (JAG1) is often associated with AGS. Cytocell's Alagille probe covers the entire JAG1 gene so that all deletions of the gene and larger deletions in the region can be detected.