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XIST LPU018
In order to achieve transcriptional balance, one X chromosome is inactivated (Xi) in every female cell. An X linked inactivation centre (Xic) at Xq13.2 is responsible for the initiation of inactivation but the exact size of the Xic is unclear although it includes the XIST gene (X-inactivation Locus). XX females with a missing XIST gene have been phenotypically associated with syndromes such as Turner Syndrome.
XIST Probe
Cat. No. LPU 018-S (5 tests)
Cat. No. LPU 018 (10 tests)
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