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The Zinc Finger protein 217 gene (ZNF217) functions as a transcription repressor for a variety of genes. It is a strong oncogene candidate which drives the 20q13.2 amplification in breast cancer, ovarian cancer and other tumours and is associated with aggressive tumour behaviour. It has been shown that the silencing of ZNF217 inhibits ovarian cancer cell growth and the invasive ability in cancer cell lines.
Cat. No. LPS 005
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