Whole chromosome painting probes

Cytocell offers a comprehensive range of single Whole Chromosome Painting probes available in the Aquarius liquid format. The probes consist of libraries of DNA sequences derived from flow-sorted chromosomes. These libraries contain sequences stretching over the entire length of the chromosome and provide superior coverage of each human chromosome.

The probes are available independently and directly labelled in either a red or a green fluorophore (Texas Red or FITC spectra respectively). They are ready to use in hybridisation solution. The kits are supplied in an economical 5 test format and come complete with DAPI counterstain.

Applications include analysis of chromosome partners involved in translocations; in identification of the chromosome of origin of marker chromosomes; confirmation of results obtained from M-FISH and SKY testing and may be of particular interest to those studying mutagenesis of human chromosomes as a result of exposure to genotoxic agents.

The probes are designed for use in fluorescence in situ hybridisation analysis of human metaphase chromosomes from cultured peripheral blood cells.

Chromoprobe Painting Combination Probe Sets (Made to order)

The Painting combinations are specially formulated mixtures of whole chromosome painting probes for different chromosomes in multiple colours. These are of particular application in genotoxicity studies for the study of breakage events. They generate excellent chromosome coverage with good fluorescence intensity and high chromosomal specificity.

Aquarius Liquid Probes

• Chromosomes 1, 2, 4 in three colours: directly labelled

** Red (Texas Red) spectrum, Green (FITC spectrum) and Blue (Aqua filter)

• Chromosomes 1,2,4 and 3,5,6 in two colours: indirectly labelled

** Red (Texas Red) spectrum and Green (FITC spectrum)

Related Products

Chromoprobe Multiprobe-System OctoChrome

The Chromoprobe Multiprobe-System OctoChrome allows the simultaneous analysis of the whole genome on one slide in one hybridisation. It combines a Multiprobe glass device of 8 squares with whole chromosome libraries. Each square of the Multiprobe carries paint probes for three different chromosomes in three different colour fluorophores.