Cytocell's Chromoprobe Multiprobe^® System (OctoChrome) combines the utility of an 8 square Multiprobe device and whole chromosome painting probes (labelled in 3 different colours), to allow all 24 chromosomes to be identified on a single slide.

The OctoChrome device therefore allows the simultaneous analysis of the whole genome on one slide in one hybridisation. Each square of the Multiprobe device carries whole chromosome painting probes for three different chromosomes in three different coloured fluorophores, red, green and blue (Texas Red, FITC and Coumarin spectra respectively) which are visible individually using the different filters or simultaneously with a DAPI/FITC/Texas Red triple filter.

The arrangement of chromosome combinations on the OctoChrome device has been designed to facilitate the identification of the non-random chromosome rearrangements found in the most common leukaemias, this is illustrated below.

The assay is supplied in a kit format of 2, 5 or 10 devices and includes hybridisation solution, counterstain, template slides, a hybridisation chamber and full instructions for use. The kit even contains a unique liquid crystal display slide surface thermometer for accurate measurement of the temperature of the denaturation surface.