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Rearrangement of the MLL gene can be detected in the leukaemia cells of approximately 85% of infants with B-ALL. Translocations involving the MLL (11q23) gene are generally associated with an increased risk of treatment failure. The most frequently observed of these translocations is the t(4;11) translocation involving the MLL gene and the AF4 gene on chromosome 4. A poor outcome for infants with ALL is strongly associated with the presence of this rearrangement in particular.
Cat. No. PMP030 (2 devices)
Cat. No. PMP031 (5 devices)
Cat. No. PMP032 (10 devices)
Cat. No. PMP033 (20 devices)
These products are only available labelled as Analyte Specific Reagents (ASR) in the USA.
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