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AML1 is fused with ETO in the t(8;21)(q22;q22) translocation. The rearrangement is observed in ~40% of AML M2 patients and less frequently in subgroups M1 and M4. Overall, 7% of AML cases demonstrate the abnormality. Three-way variants of this rearrangement and the t(3;21) (AML1/EVI1) show that juxtaposition of AML1 to the derivative chromosome is consistent and therefore the critical rearrangement.
Cat. No. PMP025 (2 devices)
Cat. No. PMP026 (5 devices)
Cat. No. PMP027 (10 devices)
Cat. No. PMP028 (20 devices)
These products are only available labelled as Analyte Specific Reagents (ASR) in the USA.
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