TeloMark Probes Brochure
Subtelomere FISH analysis is a commonly used as an adjunct to routine cytogenetic testing in order to detect small rearrangements involving the telomeric regions of chromosomes.
Patients can be referred for telomere analyses for a number of different reasons, including genetic disease, autistic disorders, unexplained mental retardation/developmental delay, recurrent miscarriages and haematological malignancies1-4.
1. de Vries et al., J Med Genet 2001;38:145-150
2. Knight et al., Am. J. Hum. Genet. 2000; 67:320-332
3. Knight et al., Eur. J Hum. Genet. 1997 Jan-Feb;5(1):1-8
4. Ravan et al., J Med Genet. 2006;43:478-489